Article
Paracrine signalling in breast cancer: Insights into the tumour endothelial phenotype.
Acta histochemica - 1 Oct 2024
Rass Atarah, Eksteen Carla, Engelbrecht Anna-Mart
Abstract excerpt
Tumour endothelial cells (TECs) are genetically and phenotypically distinct from their normal, healthy counterparts and provide various pro-tumourigenic effects. This study aimed to investigate the impact of conditioned media (CM) from non-tumourigenic MCF-12A breast epithelial cells as well as from MCF-7 and MDA-MB-231 breast cancer cells on human umbilical vein endothelial cells (HUVECs). Significant increases...
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