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STIM1-regulated exosomal EBV-LMP1 empowers endothelial cells with aggressive phenotype by activating the Akt/ERK pathway in nasopharyngeal carcinoma

2023-03-07

Abstract excerpt

<h4>Background: </h4> Stromal interaction molecule 1 (STIM1)-mediated Ca 2+ signaling regulates tumor angiogenesis in nasopharyngeal carcinoma (NPC), an Epstein-Barr virus (EBV)-related human malignancy. However, the mechanism by which STIM1 modulates the endothelial functional phenotypes contributing to tumor angiogenesis remains elusive. <h4>Methods: </h4> We explored the intercellular communication via exosoma...

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Literature Corpus work
2c850e5b-37bb-5758-9d65-3545665421ce
DOI
10.21203/rs.3.rs-2341571/v1
Open publication

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STIM1-regulated exosomal EBV-LMP1 empowers endothelial cells with aggressive phenotype by activating the Akt/ERK pathway in nasopharyngeal carcinomaDOI 10.21203/rs.3.rs-2341571/v1
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