Article

Large extracellular vesicles regulate endothelial angiogenic potential via paracrine and autocrine signaling

2025-12-19

Abstract excerpt

Angiogenesis, a process typically associated with tumor growth and development, is often linked to advanced disease and poor clinical outcomes. Tumor cells establish a pro-angiogenic microenvironment through the release of paracrine signaling mediators including extracellular vesicles (EVs). EVs have been shown to facilitate intercellular communication and encompass a diverse range of secreted vesicles, including...

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Literature Corpus work: da0abc95-8aa1-58bf-9309-bb451cdf5404
DOI: 10.64898/2025.12.17.694905

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