Article

Human heart organoids reveal a regenerative strategy for mitochondrial disease

2025-12-21

Abstract excerpt

The human heart is among the most complex tissues to replicate in vitro, with vascular, neuronal, and immune elements shaping its development and function. Here we describe cardiomorphs , self-organising human cardiac organoids that recapitulate the cellular diversity, structural organisation, vascularisation, and innervation of the myocardium and mature along a developmental trajectory from early cardiogenesis t...

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Literature Corpus work: 059201e8-0c09-55a7-896a-da5682ce60f4
DOI: 10.64898/2025.12.18.695153

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