Article
Multi-chamber cardioids unravel human heart development and cardiac defects
2022-07-16
Abstract excerpt
The number one cause of human fetal death are defects in heart development. Because the human embryonic heart is inaccessible, and the impacts of mutations, drugs, and environmental factors on the specialized functions of different heart compartments are not captured by in vitro models, determining the underlying causes is difficult. Here, we established a human cardioid platform that recapitulates the development...
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Identifiers and source
- Literature Corpus work
- 12908cbf-a05c-521a-a369-4d3253c21d1d
- DOI
- 10.1101/2022.07.14.499699