Article

ReCardioids: a robust human heart organoid platform to model doxorubicin- and radiotherapy-induced cardiotoxicity

2026-06-02

Abstract excerpt

As global cancer incidence rises, so does the population of cancer survivors, making long-term and post-treatment quality of life a central clinical concern. Despite modern improvements in treatment, cardiotoxic side effects caused by anthracycline agents and thoracic radiotherapy remain a major clinical challenge. Human iPSC-derived heart organoids offer a promising alternative to animal and 2D in vitro models,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: be3e8981-993f-5f3e-8e74-f651e8f252e9
DOI: 10.64898/2026.05.29.728705

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ReCardioids: a robust human heart organoid platform to model doxorubicin- and radiotherapy-induced cardiotoxicityDOI 10.64898/2026.05.29.728705Read

Vascularized Human Cardiac Organoids Reveal Endothelial–Cardiomyocyte Crosstalk and Mechanisms of Carfilzomib-Induced CardiotoxicitySemantic proximity Read

Human heart organoids reveal a regenerative strategy for mitochondrial diseaseSemantic proximity Read

Optimizing cardiac organoid culture to enhance maturation, viability, and cardiotoxicity assessmentsSemantic proximity Read

Advanced Cardiac Organoid Model for Studying Doxorubicin-Induced CardiotoxicitySemantic proximity Read

Multicellular Human Cardiac Organoids Transcriptomically Model Distinct Tissue-Level Features of Adult MyocardiumSemantic proximity Read

Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseasesSemantic proximity Read

Human Cardiac Organoids for Modeling Genetic Cardiomyopathy.Semantic proximity Read

Heart Slice Culture System Reliably Demonstrates Clinical Drug-Related CardiotoxicitySemantic proximity Read

The single-cell atlas of the heart reveals an unexpected erythrocyte-like cardiomyocyteSemantic proximity Read

Cardiac organoid - a promising perspective of preclinical model.Semantic proximity Read

Generation of Heart Organoids Modeling Early Human Cardiac Development Under Defined ConditionsSemantic proximity Read

Recent Advances in Generation of In Vitro Cardiac OrganoidsSemantic proximity Read