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Article

Human Cardiac Organoids for Modeling Genetic Cardiomyopathy.

Cells - 20 Jul 2020

Filippo Buono Michele, von Boehmer Lisa, Strang Jaan, Hoerstrup Simon P, Emmert Maximilian Y, Nugraha Bramasta

Abstract excerpt

Genetic cardiomyopathies are characterized by changes in the function and structure of the myocardium. The development of a novel in vitro model could help to better emulate healthy and diseased human heart conditions and may improve the understanding of disease mechanisms. In this study, for the first time, we demonstrated the generation of cardiac organoids using a triculture approach of human induced...

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Identifiers

PMID: 32698471
DOI: 10.3390/cells9071733
PMCID: PMC7409052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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