Mitochondrial cardiovascular diseases: molecular mechanisms, multi-omics exploration and therapeutic strategies

Abstract excerpt

We introduce Mitochondrial Cardiovascular Diseases (Mito-CVDs) as a novel and specific pathological category characterized by mitochondrial impairments, systematically elucidating the molecular mechanisms through mitochondrial damage, morphological remodeling and signal pathways dysregulation. By dissecting the integrative roles of mitochondrial multi-omics profiling in cardiovascular pathologies, emphasizing the...

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