Article

Association of high alpha-Klotho-levels in CSF with a later onset of cognitive impairment in patients with Parkinson´s disease

2024-01-17

Abstract excerpt

<title>Abstract</title> <p>Background: Parkinson's disease (PD) is an age-related condition characterized by substantial phenotypic variability. Consequently, pathways and proteins involved in biological aging, such as the central aging pathway comprising IGF1, alpha-Klotho, FOXO3a, and PPARγ, may potentially influence disease progression. <h4>Methods:</h4> We examined CSF levels of alpha-Klotho in 471 PD patient...

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Literature Corpus work: 058b0788-7be9-5306-b040-fcaee552696a
DOI: 10.21203/rs.3.rs-3664640/v1

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