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Role of the Insulin-like Growth Factor System in Neurodegenerative Disease

20 Apr 2024

Abstract excerpt

The insulin-like growth factor (IGF) system has paracrine and endocrine roles in the central nervous system. There is evidence that IGF signalling pathways have roles in the pathophysiology of neurodegenerative disease. This review focusses on Alzheimer’s disease and Parkinson’s disease, the two most common neurodegenerative disorders that are increasing in prevalence globally in relation to the aging population...

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PMID: 38674097
DOI: 10.3390/ijms25084512

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