Article

Understanding the pattern of cognitive decline in GBA1-related Parkinson’s Disease: a longitudinal multi-cohort study

2025-12-02

Abstract excerpt

<h4>Objective</h4> People with Parkinson’s disease (PD) who carry a pathogenic GBA1 variant (PD GBA1 ) are at higher risk of cognitive impairment than those without the variant (PD GBA1_wildtype ). To date, little is known about the pattern and evolution of cognitive decline in PD GBA1 . This multi-center study characterized the cognitive profile of PD GBA , focusing on the longitudinal trajectories and the g...

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Literature Corpus work: 26510092-dc9f-5fb3-b8a5-41e277650f23
DOI: 10.64898/2025.12.01.25341351

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