VEGFA Gene Expression Levels in Patients with Parkinson’s Disease and First-Degree Relatives

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Vascular endothelial growth factor A (VEGFA) contributes to angiogenesis and exerts neurotrophic and neuroprotective effects. Altered <italic>VEGFA</italic> expression has been implicated in neurodegenerative processes, including Parkinson´s disease (PD), yet findings from peripheral transcriptomic studies remain inconsistent. Data on individuals at increas...

Topics

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• Forkhead Box Protein O1
• Forkhead Transcription Factors
• Gene Regulatory Networks
• Intracellular Signaling Peptides and Proteins
• Lewy Bodies
• Oxidoreductases Acting on CH-NH Group Donors
• Parkinson Disease
• Prefrontal Cortex

Identifiers and source

Literature Corpus work

dca05669-e15f-53ff-8a16-0db89e446720

DOI

10.21203/rs.3.rs-8433576/v1