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Article

Klotho Is a Neuroprotective and Cognition-Enhancing Protein.

Vitamins and hormones - 1 Jan 2016

Abraham C R, Mullen P C, Tucker-Zhou T, Chen C D, Zeldich E

Abstract excerpt

In this chapter, we will describe what has been learned about Klotho and its potential functions in the brain. Klotho is localized in the choroid plexus and, to a lesser extent, in hippocampal neurons. Cognitive decline is a common issue in human aging affecting over 50% of the population. This cognitive decline can also be seen in animal models such as the Rhesus monkey. A long-term study undertaken by our lab...

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Source

Identifiers

PMID: 27125744
DOI: 10.1016/bs.vh.2016.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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