Article

Traction force dynamics during patient-derived glioblastoma neurosphere invasion in 3D Matrigel

2024-10-03

Abstract excerpt

<h4>Purpose</h4> Glioblastoma multiforme (GBM) is an aggressive brain tumor with a 5-year survival rate below 7%. Poor outcomes are driven in part by diffuse invasion into surrounding brain tissue, which limits complete surgical resection and promotes recurrence. Improved therapies require a quantitative understanding of the mechanics of GBM invasion. <h4>Methods</h4> Patient-derived GBM neurospheres were embedd...

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Literature Corpus work: 057f5b89-3b3d-5d73-91c0-0218750e4110
DOI: 10.1101/2024.10.01.616178

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