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Article

Glioblastoma Cells Use an Integrin- and CD44-Mediated Motor-Clutch Mode of Migration in Brain Tissue

4 Mar 2024

Abstract excerpt

Purpose: Glioblastoma (GBM) is an aggressive malignant brain tumor with 2 year survival rates of 6.7% (Stupp et al. in J Clin Oncol Off J Am Soc Clin Oncol 25:4127-4136, 2007; Mohammed et al. in Rep Pract Oncol Radiother 27:1026-1036, 2002). One key characteristic of the disease is the ability of glioblastoma cells to migrate rapidly and spread throughout healthy brain tissue (Lefranc et al. in J Clin Oncol Off J...

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Cell Adhesion Molecules Research
Cellular Mechanics and Interactions
Microtubule and mitosis dynamics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38737451
DOI: 10.1007/s12195-024-00799-x

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