Article

Modeling Glioma Oncostreams In Vitro: Spatiotemporal Dynamics of their Formation, Stability, and Disassembly

2023-12-15

Abstract excerpt

Glioblastoma (GBM), known for its invasive nature, remains a challenge in clinical oncology due to its poor prognosis. Only 5% of patients live past 2 years. The extensive intra-tumoral heterogeneity, combined with aggressive infiltration into surrounding healthy brain tissue limits complete resection and reduces the efficiency of therapeutic interventions. In previous studies using ex-vivo 3D explants and in-vi...

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Literature Corpus work: b9dcf75e-a838-5545-9431-8eecd8d1363c
DOI: 10.1101/2023.12.14.571722

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