Article

Altered volume-regulated anion channel activity contributes to depression and anxiety-related molecular and behavioural phenotypes in zebrafish

2026-07-27

Abstract excerpt

Major depressive disorder (MDD) is a leading cause of global morbidity and mortality. Unfortunately, a substantial proportion of patients do not respond adequately to currently available therapies, highlighting the need for new therapeutic targets. Here, we investigated the role of volume-regulated anion channel (VRAC) in depression-related phenotypes using zebrafish. Disruption of VRAC function, either by pharmac...

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Identifiers and source

Literature Corpus work: 057843e9-2902-5b88-b1d1-b3c723024efc
DOI: 10.64898/2026.07.22.740018

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