Article
Chronic unpredictable stress (CUS)-induced anxiety and related mood disorders in a zebrafish model: altered brain proteome profile implicates mitochondrial dysfunction.
PloS one - 1 Jan 2013
Chakravarty Sumana, Reddy Bommana R, Sudhakar Sreesha R, Saxena Sandeep, Das Tapatee, Meghah Vuppalapaty, Brahmendra Swamy Cherukuvada V, Kumar Arvind, Idris Mohammed M
Abstract excerpt
Anxiety and depression are major chronic mood disorders, and the etiopathology for each appears to be repeated exposure to diverse unpredictable stress factors. Most of the studies on anxiety and related mood disorders are performed in rodents, and a good model is chronic unpredictable stress (CUS). In this study, we have attempted to understand the molecular basis of the neuroglial and behavioral changes...
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