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Article

L-type calcium channels and psychiatric disorders: A brief review.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010

Casamassima Francesco, Hay Aleena C, Benedetti Alessandra, Lattanzi Lorenzo, Cassano Giovanni B, Perlis Roy H

Abstract excerpt

Emerging evidence from genome-wide association studies (GWAS) support the association of polymorphisms in the alpha 1C subunit of the L-type voltage-gated calcium channel gene (CACNA1C) with bipolar disorder. These studies extend a rich prior literature implicating dysfunction of L-type calcium channels (LTCCs) in the pathophysiology of neuropsychiatric disorders. Moreover, calcium channel blockers reduce Ca(2+)...

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Source

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PMID: 20886543
DOI: 10.1002/ajmg.b.31122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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