Article

TrkB-dependent antidepressants action involves Dlx5/6 inhibition in cortical GABAergic neurons.

2024-06-07

Abstract excerpt

<title>Abstract</title> <p>Major depressive disorder (MDD) is a complex and devastating illness that affects people of all ages. However, both the aetiology of MDD and the mechanisms of action of antidepressants are not completely understood. Many indications suggest the involvement of Parvalbumin-positive GABAergic neurons (PV-neurons) in the pathogenesis of MDD. <italic>DLX5</italic> and <italic>DLX6</italic> (...

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Literature Corpus work: 171cd93f-329d-5a81-894d-f7d93bd34d07
DOI: 10.21203/rs.3.rs-4188176/v1

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