Article

Formate reduces ischemic injury in the male heart by increasing protein <i>S</i> -nitrosation

2026-02-26

Abstract excerpt

<h4>ABSTRACT</h4> Ischemic heart disease is a leading cause of death for both men and women in the United States. We and others have demonstrated that nitric oxide (NO) signaling and associated protein S -nitrosation (SNO) play a key role in reducing ischemic injury in the heart. We also find that while females typically exhibit endogenous protection from ischemic injury, this protection is abrogated with the lo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 056bb297-3629-5dbc-9515-34e9a5f85cb1
DOI: 10.64898/2026.02.24.707768

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Formate reduces ischemic injury in the male heart by increasing protein <i>S</i> -nitrosationDOI 10.64898/2026.02.24.707768Read

The denitrosylase SCoR2 controls cardioprotective metabolic reprogrammingSemantic proximity Read

Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection FractionSemantic proximity Read

The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular healthSemantic proximity Read

Soluble epoxide hydrolase activation by S-nitrosation contributes to cardiac ischemia-reperfusion injury.Semantic proximity Read

Heart specific knockout of Ndufs4 ameliorates ischemia reperfusion injury.Semantic proximity Read

Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit with GLP-1/Glucagon AgonismSemantic proximity Read

Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure.Semantic proximity Read

Preclinical Study on the Ameliorating Effect of L-Ascorbic Acid for the Oxidative Stress of Caused by Chronic Administration of Organic Nitrates in Cardiovascular DiseasesSemantic proximity Read

Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling.Semantic proximity Read

Tissue engineering with targeted delivery of nanotized S-nitrosyl mutant of NEMO ameliorates myocardial infarction.Semantic proximity Read

Myocardial Interstitial Matrix as Novel Target for Succinic Acid Treatment Strategies during Experimental Hypobaric HypoxiaSemantic proximity Read

Human spermatozoa contain multiple targets for protein S‐nitrosylation: An alternative mechanism of the modulation of sperm function by nitric oxide?Semantic proximity Read