Article

Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit with GLP-1/Glucagon Agonism

2024-09-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Heart failure with preserved ejection fraction (HFpEF) is a significant public health concern with limited treatment options. Dysregulated nitric oxide-mediated signaling has been implicated in HFpEF pathophysiology, however, little is known about the role of endogenous hydrogen sulfide (H 2 S) in HFpEF. <h4>Objectives</h4> This study evaluated H 2 S bioavailability in p...

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Literature Corpus work: 97e7a205-b886-5af7-bd97-0a8f03565d56
DOI: 10.1101/2024.09.16.613349

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