Article

Preclinical Study on the Ameliorating Effect of L-Ascorbic Acid for the Oxidative Stress of Caused by Chronic Administration of Organic Nitrates in Cardiovascular Diseases

2021-10-19

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>The therapeutic activity of Glyceryl trinitrate (GTN) is mainly regulated by liberating nitric oxide (NO) and reactive nitrogen species (RNS). During this biotransformation, oxidative stress and lipid peroxidation inside the red blood cells (RBCs) occur. The principal objective of our research is to explain the ameliorating effect of L-ascorbic acid for the deleterio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 264c7062-ac90-507e-9df8-b1362df23524
DOI: 10.21203/rs.3.rs-968191/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Preclinical Study on the Ameliorating Effect of L-Ascorbic Acid for the Oxidative Stress of Caused by Chronic Administration of Organic Nitrates in Cardiovascular DiseasesDOI 10.21203/rs.3.rs-968191/v1Read

Molecules and Mechanisms to Overcome Oxidative Stress Inducing Cardiovascular Disease in Cancer PatientsSemantic proximity Read

Methylglyoxal in Cardiometabolic Disorders – Routes Leading to Pathology – Counterbalanced by Treatment StrategiesSemantic proximity Read

Management of oxidative stress and inflammation in cardiovascular diseases: mechanisms and challengesSemantic proximity Read

Preclinical trial of avocado pulp supplementation in an L-NAME model of cardiovascular injurySemantic proximity Read

[The role of oxidative stress in normal and pathological adaptive reactions].Semantic proximity Read

Supplementation with a bioactive melon concentrate in humans and animals: prevention of oxidative damages and fatigue in the context of a moderate or eccentric physical activitySemantic proximity Read

Improvement of cardiac dysfunction by L-arginine combined with vitamin C through restoring angiogenesis associated with NADPH/NOS/NO signal pathway in diabetic ratsSemantic proximity Read

Oxidative Stress in Cell Death and Cardiovascular DiseasesSemantic proximity Read

Ferrostatin-1 Reversed Chronic Intermittent Hypoxia-Induced Ferroptosis in Aortic Endothelial Cells via Reprogramming Mitochondrial FunctionSemantic proximity Read

Possible break-down of redox homeostasis in Beals-Hecht syndromeSemantic proximity Read

Fluoride impairs vascular smooth muscle cells via disrupting amino acids metabolismSemantic proximity Read

Free radical oxidation: a pathophysiologist’s viewSemantic proximity Read