Article

The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health

2024-11-03

Abstract excerpt

<h4>Background</h4> Xanthine oxidoreductase (XOR) is a multi-functional enzyme that metabolises purines generating uric acid and is a generator of reactive oxygen species. Both functions have been implicated in the pathogenesis of cardiovascular disease. More recently, a third function of XOR as a nitrite reductase has been identified and been shown to play a key role in the benefits of targeting the non-canonica...

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Literature Corpus work: 4e68f09e-b13e-5a60-9c88-4e4050d3244a
DOI: 10.1101/2024.11.01.621390

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