Article

Perturbed functional networks in Alzheimer’s Disease reveal opposing roles for TGIF and EGR3

2018-03-22

Abstract excerpt

While Alzheimer’s disease (AD) is the most prevalent cause of dementia, complex combinations of the underlying pathologies have led to evolved concepts in clinical and neuropathological criteria in the past decade. Pathological AD can be decomposed into subsets of individuals with significantly different antemortem cognitive decline rates. Using transcriptome as a proxy for functional state, we preselected 414 exp...

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Literature Corpus work: 816c8d3d-b802-508f-933b-f9a2fd5b8b0e
DOI: 10.1101/286674

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