Article

The construction and validation of sub-phenotype-specific genetic risk scores in systemic lupus erythematosus: a novel approach using large-scale biobank data

2025-03-12

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease with a heterogenous clinical picture. This study aimed to link genetic SLE predisposition with relevant clinical manifestations using a two-step approach. First, we identified datasets best corresponding to the 11 American College of Rheumatology 1982 (ACR-82) classification criteria for SLE using an ICD-10 code-based search in a large, public database (F...

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Literature Corpus work: 04d7ba54-1a09-5db5-acdc-f9a89fc871f8
DOI: 10.1101/2025.03.11.25323758

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