Article
Genome-wide meta-analysis with 1,590,596 individuals identifies 12 novel risk loci for systemic lupus erythematosus.
Mammalian genome : official journal of the International Mammalian Genome Society - 11 Aug 2026
Zhu Gaizhi, Su Wenting, Deng Jiahui, Zhai Bing, Gao Ran, Qiu Jinming, Gu Keqi, Bian Ziqing, Xiao He, Luan Guoming, Wang Renxi
Abstract excerpt
Systemic lupus erythematosus (SLE) is a chronic life-threatening and relapsing-remitting multisystem autoimmune disease. However, the genetic susceptibility of SLE has not been fully elucidated. This study will explore the genetic risk loci of SLE. We performed the larger multi-ancestry meta-analysis of genome-wide association study (GWAS) including 22,494 cases with SLE and 1,568,102 healthy controls....
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