Higher Genetic Risk Loads Confer More Diverse Manifestations and Higher Risk of Lupus Nephritis in Systemic Lupus Erythematosus.

doi:10.1002/art.42516

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Higher Genetic Risk Loads Confer More Diverse Manifestations and Higher Risk of Lupus Nephritis in Systemic Lupus Erythematosus.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Sept 2023

Kwon Young-Chang, Ha Eunji, Kwon Hyuk-Hee, Park Dae Jin, Shin Jung-Min, Joo Young Bin, Chung Won Tae, Yoo Dae-Hyun, Lee Hye-Soon, Kim Kwangwoo, Bae Sang-Cheol, Bang So-Young

Abstract excerpt

OBJECTIVE: Systemic lupus erythematosus (SLE) is a highly heritable complex disorder with heterogeneous clinical manifestations. In this study, we aimed to identify the genetic risk load using clinical and serological manifestations in SLE patients. METHODS: We genotyped a total of 1,655 Korean patients with SLE (n = 1,243 as a discovery set and n = 412 as a replication set) using a customized genome-wide...

Read the complete abstract on PubMed