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Article

Genetic susceptibility to systemic lupus erythematosus in the genomic era.

Nature reviews. Rheumatology - 1 Dec 2010

Deng Yun, Tsao Betty P

Abstract excerpt

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case-control, candidate gene studies as well as genome-wide association studies during the past 3 years. These techniques have identified more than 30 robust genetic associations with SLE including genetic variants of HLA and Fcγ receptor genes, IRF5, STAT4, PTPN22, TNFAIP3, BLK, BANK1, TNFSF4...

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Source

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Identifiers

PMID: 21060334
DOI: 10.1038/nrrheum.2010.176
PMCID: PMC3135416

Genes

BLK
ITGAM
PTPN22
STAT4
TNFAIP3
TNFSF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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