Article

Genetics of Systemic Lupus Erythematosus

2026-08-20

Abstract excerpt

Genetics play a significant role in the pathogenesis of systemic lupus erythematosus (SLE), as the risk among twins and siblings is substantially higher than in the general population. The genetics of SLE are complex: patients who present before puberty are more likely to have a monogenic etiology, whereas older adolescents and adult-onset SLE are more likely to have a polygenic form of disease. In addition, the m...

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Literature Corpus work: af5c63ab-d475-5f11-b869-a911b5977c9d
DOI: 10.70962/sgpi2026abstract.1

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