Article

MitoSort: robust demultiplexing of pooled single-cell genomics data using endogenous germline mitochondrial variants

2023-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Multiplexing across donors has emerged as a popular strategy to increase throughput, reduce costs, overcome technical batch effects, and improve doublet detection in single-cell genomic studies. Using endogenous genetic barcodes eliminates the need for additional experimental processing steps. Among the available choices for endogenous barcodes, the unique features of mtDNA variants render them...

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Literature Corpus work: 04bb5d2f-4b20-529f-9181-dfe80439d32b
DOI: 10.1101/2023.04.26.538392

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