Article

Cell “hashing” with barcoded antibodies enables multiplexing and doublet detection for single cell genomics

2017-12-21

Abstract excerpt

<h4>ABSTRACT</h4> Despite rapid developments in single cell sequencing technology, sample-specific batch effects, detection of cell doublets, and the cost of generating massive datasets remain outstanding challenges. Here, we introduce cell “hashing”, where oligo-tagged antibodies against ubiquitously expressed surface proteins are used to uniquely label cells from distinct samples, which can be subsequently pool...

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Literature Corpus work: dbc6b568-f8c5-5385-afe6-744ab67e181b
DOI: 10.1101/237693

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