Article

HORMA domain proteins and a Pch2-like ATPase regulate bacterial cGAS-like enzymes to mediate bacteriophage immunity

2019-07-06

Abstract excerpt

Bacteria are continually challenged by foreign invaders including bacteriophages, and have evolved a variety of defenses against these invaders. Here, we describe the structural and biochemical mechanisms of a bacteriophage immunity pathway found in a broad array of bacteria, including pathogenic E. coli and Pseudomonas aeruginosa . This pathway employs eukaryotic-like HORMA domain proteins that recognize specif...

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Literature Corpus work: 042def2e-092c-55a0-b9ac-641f54bd02cc
DOI: 10.1101/694695

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