Article
FG repeats drive co-clustering of nuclear pores and P granules in the C. elegans germline.
Development (Cambridge, England) - 15 Mar 2025
Thomas Laura L, Bodas Devavrat M, Seydoux Geraldine
Abstract excerpt
Condensates that accumulate small RNA biogenesis factors (nuage) are common in germ cells and often associate with nuclei. In the Caenorhabditis elegans germline, P granules overlay large clusters of nuclear pores and this organization has been proposed to facilitate surveillance of nascent transcripts by Argonaute proteins enriched in P granules. We report that co-clustering of nuclear pores and P granules...
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