Article
When, why and how clonal diversity predicts future tumour growth
2019-12-18
Abstract excerpt
Intratumour heterogeneity holds promise as a prognostic biomarker in multiple cancer types. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not well understood. Here we employ a spatial computational model of tumour evolution to assess when, why and how intratumour heterogeneity can be used to forecast tumour growth rate, an important predictor o...
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Identifiers and source
- Literature Corpus work
- 03ef79ad-a8eb-5ed9-a9dc-19f786c36678
- DOI
- 10.1101/2019.12.17.879270
