Article

PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease

2019-08-24

Abstract excerpt

<h4>ABSTRACT</h4> Phospholipase D3 (PLD3) is a protein of unclear function that structurally resembles other members of the phospholipase D superfamily. A coding variant in this gene confers increased risk for the development of Alzheimer’s disease (AD), although the magnitude of this effect has been controversial. Because of the potential significance of this obscure protein, we undertook a study to determine wh...

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Literature Corpus work: 03cfe223-21cb-5786-a136-0cfea42c0d24
DOI: 10.1101/746222

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