Article
PLD3 in Alzheimer's disease.
Molecular neurobiology - 1 Apr 2015
Wang Jun, Yu Jin-Tai, Tan Lan
Abstract excerpt
Rare coding variants in the phospholipase D3 (PLD3) gene, also known as HU-K4, have recently been identified to increase the risk for late-onset Alzheimer's disease (LOAD) by the whole exome sequencing (WES) in 14 large LOAD families and follow-up analyses of the candidate variants in several large independent LOAD case-control data series. PLD3 is highly expressed in the brain, especially mainly in neurons, but...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
