Article

Mechanistically Informed Prioritization of RNA–LNP Therapeutics: a Safety-by- Design Framework Integrating Virtual Patients, Synthetic Multi-Omics and Biological Consistency Assessment

2026-08-07

Abstract excerpt

<title>Abstract</title> Background RNA therapeutics are rapidly transforming precision medicine, yet their development requires simultaneous consideration of delivery efficiency, biological efficacy, and immune safety. Existing computational approaches frequently address these objectives separately and rarely connect mechanistic knowledge, artificial intelligence, formulation prioritization, and independent b...

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Literature Corpus work: 03c3a0c0-8518-51b5-b7bc-7450f99825c5
DOI: 10.21203/rs.3.rs-10513597/v1

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Mechanistically Informed Prioritization of RNA–LNP Therapeutics: a Safety-by- Design Framework Integrating Virtual Patients, Synthetic Multi-Omics and Biological Consistency AssessmentDOI 10.21203/rs.3.rs-10513597/v1Read

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