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Multiscale Predictive Cellular Modeling: Integrating Hypothesis Grammars, Digital Twins, and Multi-Omics for <em>In Silico</em> Oncology and Precision Theranostics

2025-11-03

Abstract excerpt

Predictive multiscale cellular modeling redefines precision medicine by integrating hypothesis grammars, digital twins, and integrative genomics to forecast tumor–immune dynamics, therapeutic resistance, and cellular plasticity. Hypothesis grammars translate mechanistic theories into executable agent-based models (ABMs) and hybrid ODE–PDE systems, enabling rapid in silico hypothesis testing. Patient-specific digit...

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Literature Corpus work
5fbe59ed-61e4-517a-a939-5cc266552d2b
DOI
10.20944/preprints202511.0058.v1
Open publication

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Multiscale Predictive Cellular Modeling: Integrating Hypothesis Grammars, Digital Twins, and Multi-Omics for <em>In Silico</em> Oncology and Precision TheranosticsDOI 10.20944/preprints202511.0058.v1
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