Article

Activation of Swell1 in microglia suppresses neuroinflammation and reduces brain damage in ischemic stroke

2022-03-21

Abstract excerpt

<h4>Background: </h4> Neuroinflammation and immune responses mediated by microglia are associated with brain injury after ischemic stroke, and it is novel that Cl − movement and Cl-sensitive signal pathways have been shown to be implicated in the survival and switch of inflammation patterns of immune cells. Swell1, one of the components of Volume-regulated Cl − currents (VRAC) is considered to be the main channels...

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Literature Corpus work: 03b189af-2ebd-59e5-acf8-6e0476d117df
DOI: 10.21203/rs.3.rs-1436090/v1

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