Article

Genetic and environmental contributions to eigengene expression

2024-05-15

Abstract excerpt

Multivariate network-based analytic methods such as weighted gene co-expression network analysis are being increasingly applied to human and animal gene-expression data to estimate module eigengenes (MEs). MEs represent multivariate summaries of correlated gene-expression patterns and network connectivity across genes within a module. Although this approach has the potential to elucidate the mechanisms by which mo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0372cc32-5d72-51fb-9f73-d3d6713d0f89
DOI: 10.1101/2024.05.13.593914

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic and environmental contributions to eigengene expressionDOI 10.1101/2024.05.13.593914Read

A twin analysis to estimate genetic and environmental factors contributing to variation in weighted gene co-expression network module eigengenes.Semantic proximity Read

Genomic network analysis characterizes genetic architecture and identifies trait-specific biologySemantic proximity Read

Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.Semantic proximity Read

Epistatic networks jointly influence phenotypes related to metabolic disease and gene expression in Diversity Outbred miceSemantic proximity Read

Gene expression data analysis using Hellinger correlation in weighted gene co-expression networks (WGCNA)Semantic proximity Read

Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption.Semantic proximity Read

Incorporating additive genetic effects and full LD information to discover genome-level gene-environment interactions with summary statistics of complex traitsSemantic proximity Read

Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.Semantic proximity Read

Tensor decomposition for multiple-tissue gene expression experiments.Semantic proximity Read

Interpreting genetics of gene expression: integrative architecture in Bioconductor.Semantic proximity Read

Synchronized genetic activities in Alzheimer’s brains revealed by heterogeneity-capturing network analysisSemantic proximity Read

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins.Semantic proximity Read