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Synchronized genetic activities in Alzheimer’s brains revealed by heterogeneity-capturing network analysis

2020-01-29

Abstract excerpt

It is becoming increasingly evident that the efficacy of single-gene computational analyses for complex traits is nearly exhausted and future advances hinge on unraveling the intricate combinatorial interactions among multiple genes. However, the discovery of modules of genes working in concert to manifest a complex trait has been crippled by combinatorial complexity, genetic heterogeneity, and validation biases....

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Literature Corpus work
1df75e48-5607-5827-8d83-39c5c785dcec
DOI
10.1101/2020.01.28.923730
Open publication

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Synchronized genetic activities in Alzheimer’s brains revealed by heterogeneity-capturing network analysisDOI 10.1101/2020.01.28.923730
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