Article
Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice.
Genetics - 1 Jun 2017
Tyler Anna L, Ji Bo, Gatti Daniel M, Munger Steven C, Churchill Gary A, Svenson Karen L, Carter Gregory W
Abstract excerpt
Genetic studies of multidimensional phenotypes can potentially link genetic variation, gene expression, and physiological data to create multi-scale models of complex traits. The challenge of reducing these data to specific hypotheses has become increasingly acute with the advent of genome-scale data resources. Multi-parent populations derived from model organisms provide a resource for developing methods to...
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