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Article

Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption.

PloS one - 1 Jan 2013

Vanderlinden Lauren A, Saba Laura M, Kechris Katerina, Miles Michael F, Hoffman Paula L, Tabakoff Boris

Abstract excerpt

To identify brain transcriptional networks that may predispose an animal to consume alcohol, we used weighted gene coexpression network analysis (WGCNA). Candidate coexpression modules are those with an eigengene expression level that correlates significantly with the level of alcohol consumption across a panel of BXD recombinant inbred mouse strains, and that share a genomic region that regulates the module...

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Identifiers

PMID: 23894363
DOI: 10.1371/journal.pone.0068878
PMCID: PMC3720886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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