Article

Transcriptomics of acute DENV-specific CD8+ T cells does not support qualitative differences as drivers of disease severity

2021-09-03

Abstract excerpt

While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has been hypothesized that the more severe form of the disease (dengue hemorrhagic fever, DHF) is associated with altered T cell responses. To address this question, we d...

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Literature Corpus work: 0345c999-8eb2-5630-8c35-317f786c6aa0
DOI: 10.1101/2021.09.01.21262833

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