Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease Severity

14 Apr 2022

Abstract excerpt

While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has been hypothesized that the more severe form of the disease (dengue hemorrhagic fever, DHF) is associated with altered T cell responses. To address this question, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35455361
DOI: 10.3390/vaccines10040612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease SeverityPMID 35455361Read ↗

Transcriptomics of acute DENV-specific CD8+ T cells does not support qualitative differences as drivers of disease severitySemantic proximity Read ↗

Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue DiseaseSemantic proximity Read ↗

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infectionSemantic proximity Read ↗

Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe dengueSemantic proximity Read ↗

Early transcriptomic host response signatures in the serum of dengue patients provides insights into clinical pathogenesis and disease severitySemantic proximity Read ↗

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infectionSemantic proximity Read ↗

Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengueSemantic proximity Read ↗

Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profilesSemantic proximity Read ↗

Global and cell type-specific immunological hallmarks of severe dengue progressionSemantic proximity Read ↗

A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge modelsSemantic proximity Read ↗

Patterns of Host Genome–Wide Gene Transcript Abundance in the Peripheral Blood of Patients with Acute Dengue Hemorrhagic FeverSemantic proximity Read ↗

Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.