Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe dengue

27 Jun 2025

Abstract excerpt

Development of strategies to prevent severe dengue has been challenging, partly by our incomplete understanding of a protective immune response after dengue virus (DENV) infection. To define adaptive immune signatures associated with protection from hospitalized dengue , we performed in-depth single-cell immunoprofiling and quantified DENV-specific T cells in subclinical or hospitalized dengue-infected children....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40580952
DOI: 10.1016/j.chom.2025.06.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe denguePMID 40580952Read ↗

Global and cell type-specific immunological hallmarks of severe dengue progressionSemantic proximity Read ↗

Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.Semantic proximity Read ↗

Integrated single-cell analysis reveals interferon-driven immune signatures in a DENV1 human infection modelSemantic proximity Read ↗

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infectionSemantic proximity Read ↗

Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profilesSemantic proximity Read ↗

Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengueSemantic proximity Read ↗

Transcriptomics of Acute DENV-Specific CD8+ T Cells Does Not Support Qualitative Differences as Drivers of Disease SeveritySemantic proximity Read ↗

Transcriptomics of acute DENV-specific CD8+ T cells does not support qualitative differences as drivers of disease severitySemantic proximity Read ↗

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infectionSemantic proximity Read ↗

Human T Cell Response to Dengue Virus InfectionSemantic proximity Read ↗

Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from IndiaSemantic proximity Read ↗

Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.