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Updates on genetics in systemic sclerosis

15 Jun 2021

Abstract excerpt

Systemic sclerosis (SSc) is a complex disease, in which an interaction of genetic and environmental factors plays an important role in its development and pathogenesis. A number of genetic studies, including candidate gene analysis and genome-wide association study, have found that the associated genetic variants are mainly localized in noncoding regions in the expression quantitative trait locus and influence...

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PMID: 34130729
DOI: 10.1186/s41232-021-00167-6

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