Article
Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes
29 Sept 2014
Abstract excerpt
Systemic sclerosis (SSc) is a fibrotic and autoimmune disease characterized clinically by skin and internal organ fibrosis and vascular damage, and serologically by the presence of circulating autoantibodies. Although etiopathogenesis is not yet well understood, the results of numerous genetic association studies support genetic contributions as an important factor to SSc. In this paper, the major genes of SSc...
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