Article
Recent advances in elucidating the genetic basis of systemic sclerosis.
Current opinion in rheumatology - 1 Nov 2022
Villanueva-Martín Gonzalo, Martín Javier, Bossini-Castillo Lara
Abstract excerpt
PURPOSE OF REVIEW: Systemic sclerosis (SSc) is a complex autoimmune disorder that affects the connective tissue and causes severe vascular damage and fibrosis of the skin and internal organs. There are recent advances in the field that apply novel methods to high throughput genotype information of thousands of patients with SSc and provide promising results towards the use of genomic data to help SSc diagnosis...
Topics
- Autoimmune Diseases
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- Humans
- Scleroderma, Systemic